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The Specific Inhalation Challenge (SIC) is defined as a diagnosis tool to assess airway responsiveness to "sensitizing" substances as opposed to nonspecific stimuli such as pharmacological agents (i.e. histamine, methacholine), cold air and exercise.〔.〕 Subjects are exposed to a suspected occupational agent in a controlled way under close supervision in a hospital laboratory. The specific inhalation challenges has been considered as the gold standard in confirming the diagnosis of occupational asthma. == SIC methods == One of the steps of SIC is to perform a challenge with the suspected asthmagen. Then, FEV1 is subsequently measured using another device and compared to a baseline. A positive response is usually a decrease in baseline FEV1 of 15 to 20 percent. 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Specific inhalation challenge」の詳細全文を読む スポンサード リンク
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