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Specific inhalation challenge
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Specific inhalation challenge : ウィキペディア英語版
Specific inhalation challenge
The Specific Inhalation Challenge (SIC) is defined as a diagnosis tool
to assess airway responsiveness to "sensitizing" substances as opposed to
nonspecific stimuli such as pharmacological agents (i.e. histamine, methacholine),
cold air and exercise.〔.〕
Subjects are exposed to a suspected occupational agent in a controlled way under close supervision
in a hospital laboratory. The specific inhalation challenges has been considered as the
gold standard in confirming the diagnosis of occupational asthma.

== SIC methods ==
One of the steps of SIC is to perform a challenge with the suspected asthmagen.
Then, FEV1 is subsequently measured using another device and compared to a baseline.
A positive response is usually a decrease in baseline FEV1 of 15 to 20 percent.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Specific inhalation challenge」の詳細全文を読む



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